Leucoderma Vs Vitiligo: Know the Differences

Leucoderma Vs Vitiligo

Leucoderma Vs Vitiligo: Leucoderma and Vitiligo are both skin disorders distinguished by white spots, however, their causes differ. Leucoderma is a comprehensive word that encompasses all causes of skin depigmentation, including those caused by Leucoderma vs Vitiligo, such as accidents, burns, or chemical exposure. Vitiligo is a type of autoimmune illness in which the body assaults pigment-producing cells, resulting in distinctive white patches.

blog banner blog banner

Difference Between Leucoderma and Vitiligo

Leucoderma and vitiligo are both skin conditions characterized by depigmentation, but they have some key differences. Listed below are the differences between the two conditions:





Refers to white patches on the skin.

A chronic skin condition characterized by loss of melanin.


Various factors including fungal infections, injuries, or autoimmune disorders.

Primarily autoimmune disorder attacking melanocytes.

Extent of Pigmentation Loss

May not be as extensive or uniform.

Patches tend to be defined and symmetric.

Associated Conditions

Less strongly associated with other autoimmune diseases.

Often associated with autoimmune diseases like thyroid disorders.

Age of Onset

Can occur at any age, including later in life.

Often starts before the age of 20.


Patches may not follow a symmetric pattern.

Typically appears symmetrically on both sides of the body.


May remain stable or regress spontaneously.

Tends to progress over time, with existing patches enlarging.

Response to Treatment

Some forms may respond better to treatment.

Difficult to treat, with treatments aiming to slow down progression.

Genetic Factors

May not have a strong genetic predisposition.

Stronger genetic component, with a higher likelihood in individuals with a family history.

Association with Sun Exposure

Patches may not show pronounced changes with sun exposure.

Patches may become more noticeable with sun exposure.

Browse Best Scrubs Collection

What is Leucoderma?

Leucoderma is caused by external factors that damage melanocytes, the cells that produce melanin. This can happen from cuts, burns, chemical exposure, or certain inflammatory skin diseases. The white patches tend to be smaller and localized to the area of injury.

Key Features of Leucoderma:

  • Leucoderma causes patchy, white patches on the skin, often with irregular borders. These patches can vary in size and appear anywhere on the body.
  • Cause: The exact cause of leucoderma is unknown. However, it's believed to be linked to several factors, including autoimmune reactions, chemical exposure, and genetic predisposition.
  • Impact: While not physically harmful, leucoderma can cause significant emotional distress and social stigma, especially in communities with specific beauty standards related to skin color.
  • Treatment: There's no permanent cure for leucoderma, but treatments can help manage the condition and improve the appearance of the patches. These include corticosteroid creams, light therapy, and surgical procedures in severe cases.

blog banner blog banner

What is Vitiligo?

Vitiligo, on the other hand, is an autoimmune illness in which the immune system targets and kills melanocytes. This results in white spots that can occur anywhere on the body, usually symmetrical on both sides. Vitiligo can also damage hair and mucous membranes.

Key Features of Vitiligo:

  • Vitiligo causes smooth, white patches on the skin with well-defined borders. These patches typically appear symmetrically on both sides of the body, often on areas exposed to sunlight like the face, hands, and arms.
  • Cause: Vitiligo is an autoimmune disease where the body's immune system attacks the pigment-producing cells (melanocytes) in the skin. The exact reason for this attack is still under investigation.
  • Impact: Similar to leucoderma, vitiligo can cause psychological distress and social stigma. Additionally, it can lead to increased sun sensitivity in the affected areas.
  • Treatment: As with leucoderma, there's no permanent cure for vitiligo. However, treatments can help manage the condition and pigment the affected areas. These include corticosteroid creams, calcineurin inhibitors, light therapy, and depigmentation therapy (in widespread cases).

Shop Best Lab Coats from Here!

Similarities Between Leucoderma and Vitiligo

  • leucoderma and vitiligo, both are distinguished by the loss of pigmentation in affected regions of the skin.
  • Both disorders can have a substantial psychological impact on people because of the obvious nature of the depigmented patches and the possible social shame associated with the changed look.
  • Both disorders are frequently diagnosed by clinical examination, medical history review, and, in certain cases, skin biopsies to confirm the lack of melanocytes.
  • Both disorders can be treated with topical corticosteroids, phototherapy, immunomodulators, and, in extreme situations, surgical treatments such as skin grafting.
  • Both illnesses are chronic and may need long-term treatment to manage symptoms and prevent development.
  • Both leucoderma and vitiligo can reoccur after effective therapy, demanding continued monitoring and care.

While both Leucoderma and Vitiligo present with white spots on the skin, their origins and features differ greatly. Leucoderma, a wider word, refers to any disorder that causes skin pigmentation loss, including Vitiligo. However, Vitiligo is an autoimmune illness in which the body assaults pigment-producing cells, resulting in well-defined, symmetrical patches that can develop anywhere. In contrast, leucoderma is frequently caused by external causes such as injury, burns, or chemical exposure, resulting in localized, uneven patches that are generally concentrated around the afflicted region. Understanding the difference between Leucoderma and Vitiligo is critical for accurate diagnosis and treatment.

Check out More Articles
Difference Between Cartilage and Bone
Difference Between Endocrine and Exocrine Glands
Difference Between Cell Wall and Cell Membrane


What is Leucoderma?

Leucoderma, also known as white patches, is a skin disorder characterized by the partial loss of pigmentation, resulting in white spots on the skin.

What is Vitiligo?

Vitiligo is a chronic skin condition where patches of skin lose their pigment, resulting in irregular white patches that may vary in size and location.

How do Leucoderma and Vitiligo differ?

While both conditions involve the loss of skin pigmentation, Leucoderma typically refers to localized patches, whereas Vitiligo often involves larger, more widespread areas of depigmentation.

Are there similarities between Leucoderma and Vitiligo?

Yes, both Leucoderma and Vitiligo involve the loss of melanin, the pigment responsible for skin color. Additionally, both conditions can occur at any age and affect individuals of any skin tone.

What are the common causes of Leucoderma and Vitiligo?

The exact cause of both conditions is not fully understood, but they are believed to involve a combination of genetic, autoimmune, and environmental factors.