Bilastine vs Fexofenadine in Urticaria: Know the Differences

Bilastine vs Fexofenadine in Urticaria

Difference between Bilastine vs Fexofenadine in Urticaria: Bilastine and Fexofenadine are both second-generation antihistamines prescribed to treat Urticaria. By preventing histamine receptors from functioning, they reduce swelling and itching. Whereas Bilastine may begin acting in as little as 1-2 hours and is prescribed for those 12 years of age and above, Fexofenadine normally takes effect in 1-3 hours and is safe for youngsters as young as 6. Both medications have no sedative effects and provide relief for roughly 24 hours. The safety profiles are good, however expectant or nursing mothers should see a healthcare professional. When deciding between Bilastine and Fexofenadine, one should ultimately take availability, cost, and individual response into account.

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Difference between Bilastine vs Fexofenadine in Urticaria

Bilastine and Fexofenadine effectively inhibit histamine receptors to provide minimally sedative, 24-hour relief from Urticaria. Bilastine takes 1-2 hours to start functioning and is recommended for those 12 years of age and above, but Fexofenadine takes 1-3 hours to start working and is suitable for youngsters as young as 6. The table below provides the differences between Bilastine and Fexofenadine in Urticaria.

Feature

Bilastine

Fexofenadine

Onset of Action

Typically starts working within 1-2 hours

Usually starts working within 1-3 hours

Duration of Action

Provides 24-hour relief

Provides 24-hour relief

Age Restrictions

Approved for ages 12 and above

Approved for ages 6 and above

Sedation

Non-sedating

Non-sedating

Safety Profile

Generally well-tolerated, minimal side effects

Generally well-tolerated, minimal side effects

Drug Interactions

Low potential for interactions

Low potential for interactions

Pregnancy and Lactation

Considered relatively safe with consultation

Considered relatively safe with consultation

Availability

Available in tablets and oral solutions

Available in tablets, capsules, and oral suspension

Cost

Cost may vary depending on brand and formulation

Cost may vary depending on brand and formulation



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What is Bilastine?

Bilastine is a second-generation antihistamine that treats allergic rhinitis (hay fever) and chronic Urticaria (hives). It relieves symptoms including itching, sneezing, runny nose, and watery eyes by inhibiting the body's histamine receptors. Because of its well-known non-sedating qualities, Bilastine is appropriate for use during the day without making you feel sleepy. Usually, it is given orally as an oral solution or tablet form.

Features of Bilastine

  • Selective H1 Receptor Antagonist: Billastine reduces allergic reaction symptoms without inducing a considerable amount of drowsiness by blocking histamine H1 receptors.
  • Non-Sedating: Billastine is well-known for not being a sedative, which means that it is safe to use during the day and usually doesn't make you feel sleepy or impair your cognitive abilities.
  • Fast Onset of Action: After consumption, it starts to act quite rapidly, with symptom relief frequently occurring within 1-2 hours.
  • Long Duration of Action: Bilastine offers convenient once-daily dosage relief from allergy symptoms for a full 24-hour period.
  • Minimal Drug Interactions: When used with other medications, it has a low potential for interactions, which lowers the risk of side effects or consequences.

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What is Fexofenadine?

Fexofenadine is a type of antihistamine that belongs to the second generation and is used to treat allergic disorders like hay fever and chronic Urticaria, or hives. It functions by inhibiting the body's histamine receptors, which lessens allergic reaction symptoms like sneezing, itching, runny or blocked noses, and watery eyes. Due to Fexofenadine's well-known non-sedating qualities, it is appropriate for use during the day without making one feel sleepy. It is usually used orally and comes in a variety of forms, such as tablets, capsules, and oral suspension.

Features of Fexofenadine

  • Non-Sedating: Its well-known non-sedating qualities allow it to be used during the day without making one feel sleepy or affecting one's ability to think clearly.
  • Fast Onset of Action: Fexofenadine usually begins to operate one to three hours after consumption, offering comparatively rapid relief from allergy symptoms.
  • Long Duration of Action: It provides a convenient once-daily dosage by providing 24-hour relief from allergy symptoms.
  • Few Drug Interactions: When taken with other medications, Fexofenadine has a low potential for interactions, which lowers the possibility of side effects or consequences.
  • Appropriate for a Range of Age Groups: It can be used to treat a wide range of patients, including adults and infants as young as six months old.

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Similarities between Bilastine and Fexofenadine in Urticaria

  • Antihistamine Action: Bilastine and Fexofenadine are second-generation antihistamines that relieve Urticaria symptoms such as itching, swelling, and redness by inhibiting histamine receptors in the body.
  • Non-Sedating: These drugs are well-known for not being sedatives, which means they usually don't make you feel sleepy or affect your ability to think clearly. This enables them to be used during the day without interfering with regular activities.
  • Fast Onset of Action: Both Fexofenadine and Bilastine often begin to act comparatively quickly after consumption, with symptom alleviation frequently starting 1-3 hours later.
  • Long Duration of Action: Both medications offer relief for about 24 hours, making once-daily dosing convenient and enabling long-term management of Urticaria symptoms.

In conclusion, Bilastine and Fexofenadine are second-generation antihistamines used to treat Urticaria. They differ in their cost, age limitations, and mode of action, but their efficacy and safety profiles are similar. While Fexofenadine is approved for use in adults and children 6 years of age and up, Bilastine may begin to function slightly faster and is approved for use in adults and children 12 years of age and up. The price of the two drugs may differ.

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FAQ's

What is Urticaria?

Urticaria, commonly known as hives, is a skin condition characterized by itchy, raised welts or bumps on the skin. It can be triggered by allergic reactions, infections, medications, or other factors.

How do Bilastine and Fexofenadine work in treating Urticaria?

Both Bilastine and Fexofenadine are second-generation antihistamines that work by blocking histamine receptors in the body. Histamine is a chemical released during allergic reactions, and blocking its action helps alleviate symptoms such as itching, swelling, and redness associated with Urticaria.

Are Bilastine and Fexofenadine sedating?

No, both Bilastine and Fexofenadine are considered non-sedating antihistamines. They do not typically cause drowsiness or impair cognitive function, making them suitable for daytime use.

How long does it take for Bilastine and Fexofenadine to start working?

Bilastine may begin to function 1-2 hours after consumption, but Fexofenadine often does so within 1-3 hours of administration.

How long do the effects of Bilastine and Fexofenadine last?

Both medications allow for once-daily administration and offer relief for about 24 hours.

Are there any age restrictions for using Bilastine and Fexofenadine?

While Fexofenadine is approved for use in children and adults 6 years of age and above, Bilastine is only approved for use in adults 12 years of age and up.